Are Some Cases of Autism Actually Subclinical, Congenital Attenuated Rubella Syndrome? A Collection of Data and Questions for Consideration and Review by the IOM Immunization Safety Review Committee
نویسنده
چکیده
Overview of Persistent Rubella Infection and Autism Induction in Pregnancy Idea 3 Why Might Vaccine-Strain Rubella Virus Persist in Some Females? 3 Questions about RA27/3 Strain of Rubella Vaccine 4 What Data in the Literature & What Facts May Support these Ideas? 4-9 Concluding Remarks & Requests 9 A Final Data Point & Questions 10 References 11 Appendix A: Information provided from CBER/FDA on the origin and history of rubella and measles vaccines 13
منابع مشابه
Immunization Safety Review: Vaccines and Autism
Immunization to protect children and adults from infectious diseases is one of the greatest achievements of public health. Immunization is not without risks, however. It is well established, for example, that the oral polio vaccine on rare occasion has caused paralytic polio and that vaccines sometimes produce anaphylactic shock. Given the widespread use of vaccines, state mandates requiring va...
متن کاملتعیین فراوانی سندرم سرخجه مادرزادی متعاقب واکسیناسیون سرخک ـ سرخجه تصادفی زنان باردار در سال 1382
Background & Aim: Rubella vaccine contains live attenuated virus that can be transmitted to fetus causing severe abnormalities in the fetus during pregnancy. However there isn't enough studies to show any congenital rubella syndrome(CRS) in these cases, yet. During mass campaign for Measles-Rubella vaccination in December 2003 in Iran, many pregnant women were vaccinated accidently. In this...
متن کاملRubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis
Background: Rubella infection with in the first trimester of pregnancy may lead to adverse pregnancy outcomes. The present study was conducted to evaluate the immunity against rubella among pregnant Iranian women. Materials and Methods: The steps of meta-analyses were conducted based on the PRISMA guidelines. To review the associated English and Persian literature, a comprehensive search was co...
متن کاملSequence and Phylogenetic Analysis of Wild Type Rubella virus isolated in Iran
Background and Aims: Rubella virus is a human pathogen that causes congenital rubella syndrome (CRS) when infection occurs during early pregnancy. Vaccination programs have been remarkably successful in controlling natural rubella infection and CRS. Moreover, ongoing surveillance for all cases of rubella and CRS is a vital component of a prevention program. Although the WHO recommends the use o...
متن کاملEvaluation of Antibodies against Rubella Virus in a Mass Campaign Vaccination in Tehran, Iran
Background and Aims: Vaccine is available, but fetal infection with rubella virus is still a main cause of congenital birth defects and mental retardation in many countries. Mass vaccination campaigns and Expanded Program of Immunization (EPI) have increased vaccine coverage in the world with a substantial impact on the reduction of rubella infections, such as Congenital Rubella Syndrome (CRS)....
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تاریخ انتشار 2004